Error on Plesk for Windows server: Module "IsapiCachesModule" could not be found

Started by senthil, May 26, 2025, 02:40 AM

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senthil

Symptoms
  • On a Plesk for Windows server, instead of the login page, users will see a blank screen with the title "500 Internal
    server error".
  • The following error can now be seen instead of the blank screen after the steps below are executed:
    • Edit C:\Program Files (x86)\Plesk\admin\htdocs\web.config and set
      errorMode="DetailedLocalOnly" then save the file.
    • Open the Plesk login page again within the server browser.
      HTTP Error 500.0 - Internal Server Error
      Module "IsapiCachesModule" could not be found
  • An antivirus has quarantined files from the C:\Windows\System32\inetsrv folder.

Cause
DLL system files were infected from an unknown source.

Resolution
Contact Microsoft Support to obtain a genuine copy of the missing files.